NOT KNOWN DETAILS ABOUT FENTANYL TOXICITY SIGNS AND SYMPTOMS

bosentan will lessen the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Coadministration of fentanyl with CYP3A4 inducers could lead on into a decrease in fentanyl plasma concentrations, deficiency of efficacy or, quite possibly, advancement of the withdrawal syndrome inside a aff